Copper(II) Naproxenate

Copper(II) naproxenate is a coordination compound with the formula Cu(C14H13O3)2. It is currently being researched as a alternative for the base molecule naproxen, which is a NSAID compound. The copper complex, like many other NSAID copper(II) complexes could offer better anti-inflammatory properties with less negative side effects.

Structure
In copper(II) naproxenate, the copper center in each molecule forms five coordination bonds with the oxygen, which forms a square pyramidal structure.

Synthesis
Copper(II) naproxenate can be made by reacting naproxen with sodium carbonate or sodium bicarbonate at room temperature to form sodium naproxenate.

Sodium naproxenate can then be reacted with copper(II) sulfate in solution. Bright Green copper(II) naproxenate will precipitate out of solution.